Levodopa, the gold-standard treatment for Parkinson’s disease, is often given alongside medicines called catechol-O-methyltransferase inhibitors (COMT-Is) that are designed to boost its efficacy — but a new study suggests these medications may also reduce the amount of levodopa available to reach the brain. Specifically, the data suggest treatment with…

A new support group called Angels Embrace aims to offer education, connection, and emotional support for people affected by neurodegenerative conditions such as Parkinson’s disease and dementia. The program is being offered by Angels on Call Homecare, a company recognized for providing specialized Parkinson’s and dementia care at…

I didn’t expect just how much my relationship with my late uncle Brandon would change over the years. When I was a kid, he was always the one who got everyone going in the morning. I remember us kids staying up too late playing Nintendo, thinking we were sneaky. No…

A small, lab-made molecule called SK-129 reduced the formation of toxic clumps of the alpha-synuclein protein, a hallmark of Parkinson’s disease, a study found. SK-129 was able to cross the blood-brain barrier – a semipermeable membrane that protects the brain and central nervous system – and prevent damage caused…

In the U.S., the total cost of Parkinson’s disease — including direct medical costs and lost productivity from patients and caregivers — was more than $82 billion in 2024, according to a new report from The Michael J. Fox Foundation for Parkinson’s Research (MJFF). The findings build on…