Low dopamine levels disrupt nerve circuits in the brain in Parkinson’s disease — but a new study indicates that different brain circuits show different, even opposite, types of changes. The study’s findings shed new light on how brain circuits are affected by Parkinson’s. The researchers said their data also suggest…

Higher blood levels of a specific ratio between two fats, called ceramides, may help identify people with Parkinson’s disease who are more likely to develop thinking and memory problems, according to a new study. A higher Cer 24:1/Cer 24:0 ratio was closely associated with worsening cognitive impairment and remained…

When my uncle Brandon came home one time from a Parkinson’s appointment, he was quieter than usual. The news wasn’t what we had hoped for. His symptoms had gotten worse, and, even though he rarely complained, our family could tell it had been a tough day. He sat…

I’ve never been much of a gun person. Perhaps that’s why it took me so long to understand the shotgun that recently found its way back to my family. My father told me it originally belonged to my grandfather Howard’s uncle, Edward Bernard Mooney. The serial number indicates it was…

Alzheimer’s-related brain changes may not be a major contributor to earlier cognitive problems in people with Parkinson’s disease who have not developed dementia, a new study suggests. Researchers found that blood levels of phosphorylated tau-217 (p-tau217), a blood marker of early Alzheimer’s disease, were not clearly associated with…