Scientists have developed an experimental gene therapy with the potential to treat early-onset Parkinson’s disease associated with PRKN gene mutations, according to a new preclinical study. Delivery of the gene therapy carrying a functional version of the PRKN gene into the brains of two mouse…
Discussion
I recently started seeing a new neurologist after the doctor I’ve had since my Parkinson’s diagnosis moved out of state. This has been a big deal for me; I even devoted a column to how much I’ll miss her. I loved my doc. She saw me through 12-plus…
GT-02287, an oral Parkinson’s disease therapy from Gain Therapeutics, showed promising results in a Phase 1b trial. Over three months of treatment, patients had lower levels of DOPA decarboxylase (DDC) in their cerebrospinal fluid — a biomarker linked to Parkinson’s activity. Motor function remained stable over five months of treatment.
Young adults with autism may show abnormalities in the activity of dopamine transporters — proteins that recycle dopamine after its release in the brain — that are commonly associated with Parkinson’s disease, according to a recent study. Using dopamine transporter imaging scans, or DaTscan, researchers identified abnormalities in…
Discussion
Women’s History Month, celebrated each March, originated in 1978 when an educational task force in Santa Rosa, California, set out to highlight women’s contributions to society. This month also serves as a time for reflection on persistent issues such as the exclusion of women from textbooks and research. Historically,…
GEN Pharmaceuticals has received ethical approval from an accredited medical research ethics committee in the Netherlands to conduct a small clinical trial testing SUL-238, its investigational medication for Parkinson’s disease. With this approval, the company will activate a clinical site in Groningen in the northern Netherlands with patient…
Becoming educated and informed about Parkinson’s is a good first step. Here you’ll find general information about the disease, including diagnosis, symptoms, and causes.
It helps to know others have been where you are now. Here’s a collection of our columnists’ words of wisdom to help you along on your Parkinson’s journey.
There is no cure for Parkinson’s yet, but there are treatments that can help manage the disease. Learn more about current therapeutic approaches here.
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