Biogen and Denali Therapeutics have ended their clinical development of BIIB122 for people with idiopathic Parkinson’s disease after the experimental therapy failed to slow disease progression in a Phase 2b trial. The decision follows results from the Phase 2b LUMA study (NCT05348785), which compared BIIB122 (also…
Discussion
A team of researchers in Germany has developed an immuno-infrared sensor (iRS) designed to detect misfolded alpha-synuclein, a protein linked to Parkinson’s disease, in body fluids including blood and the fluid that surrounds the brain and spinal cord. The researchers say the technology could one day support earlier diagnosis,…
Discussion
As you probably know by now if you’ve been reading my column, my late uncle Brandon liked to stay on the move. His career involved hands-on work, building things from the ground up, and figuring out problems on his own. That hardworking mentality wasn’t just part of his job. It…
Discussion
Herantis Pharma will use a system based on smartphone technology to measure symptom changes in a Phase 2 trial testing its Parkinson’s disease treatment HER-096. Researchers will use Indivi’s digital biomarker platform alongside conventional clinical assessments to help researchers detect early changes in motor and cognitive function in…
Discussion
My husband, Arman, who has early-onset Parkinson’s disease, and I don’t get to the movies very often. Instead, we prefer to wait and stream films from the comfort of home. But when the movie “Wicked” was released in theaters in November 2024, there was no way our small TV…
Discussion
The first participant has been dosed in Vertero Therapeutics’ Phase 1b clinical trial testing VT-5006, an investigational, gut-directed oral small molecule being developed for Parkinson’s disease. The Phase 1b clinical trial (NCT07310264) is still recruiting adults ages 40-80 with early- or moderate-stage…
Becoming educated and informed about Parkinson’s is a good first step. Here you’ll find general information about the disease, including diagnosis, symptoms, and causes.
It helps to know others have been where you are now. Here’s a collection of our columnists’ words of wisdom to help you along on your Parkinson’s journey.
There is no cure for Parkinson’s yet, but there are treatments that can help manage the disease. Learn more about current therapeutic approaches here.
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